Deb & Jenny B: That's totally awesome. I hope the half-marathon goes great.
Not everyone has a lot of time or money to give back. They always seem to be in short supply. But I bet that everyone reading this has access to a computer.
Enter Folding@Home, one of the most painless ways you can make a contribution to medical science. It's a way I give back every day.
Folding@Home is an attempt out of Stanford to let the public help solve computational biology problems. Biologists have collected tons and tons of data about how proteins fold, but don't have the computational power to sort out what it all means. So the Folding@Home project uses people's home computers to crunch numbers and report back.
For the user, the experience is extremely simple. You go to
the Folding@Home website and follow the links to download the client. Pick a user name, join a team (might I suggest the Nerdfighters Team, 201140?), and let the program run. It runs in the background and uses computational power your computer has free at the moment to do it's thing. If you drop the program in the Startup folder (Windows), you never have to think about it again: every time you boot your computer, it'll start up. When it's done with one data set, it'll phone home and get a new one. You can even set it up on a PS3.
Understanding how proteins fold is a really big deal. Lots of diseases, including Alzheimer's, ALS, Huntington's, and Parkinson's disease, are thought to involve mis-folded proteins.
I participate in this project because I know how important it is. I'm not part of any lab that benefits directly from this data, but I
can say that the processing power donated by the public through this program is hugely valuable. It makes a real difference. And that difference is aimed at some of the scariest problems biology faces.